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Furazolidone-containing modified dual therapy dual therapy versus standard quadruple therapy for Helicobacter pylori eradication

Efficacy and safety of furazolidone-containing modified dual therapy in eradication for Helicobacter pylori

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026675
Enrollment
Unknown
Registered
2019-10-18
Start date
2018-06-01
Completion date
Unknown
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infections

Interventions

Experimental group:Esomeprazole + Furazolidone Tablets
Control group:Esomeprazole + bismuth potassium citrate granules + Amoxicillin Capsules + Furazolidone Tablets

Sponsors

Nanfang Hospital, Southern Medical University, Guangzhou, China.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 70 years, male and female; 2. Clinical diagnosis of Helicobacter pylori infection; 3. C13 insufflation test or rapid urease test is positive.

Exclusion criteria

Exclusion criteria: (1) Antibiotics, PPI, expectorant or non-steroidal anti-inflammatory drugs have been used within one month; (2) Pregnancy or lactation; (3) Allergic to the drugs used in the study; (4) Combined with a serious underlying disease or other disease that may lead to treatment failure; (5) With a history of gastrointestinal surgery, or a recent history of other types of surgery; (6) Having a family history of genetic disease, a history of mental illness, etc.; (7) Subjects are participating in other research topics; (8) The investigator believes that other reasons are not suitable for continuing clinical trials.

Design outcomes

Primary

MeasureTime frame
the eradication rate of Helicobacter pylori;

Countries

China

Contacts

Public ContactBai Yang

Nanfang Hospital, Southern Medical University

13925001665@163.com+86 13925001665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026