retinoblastoma
Conditions
Interventions
Tumor Initial diagnosis group:Protein extracted from urine
Normal controls:Protein extracted from urine
Non-tumor group of ophthalmic diseases:Protein extracted from urine
Tumor cure group:Protein extracted from urine
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for children with RB: (1) Chinese Han children aged 0-18; (2) Children treated and/or operated on at Beijing Children's Hospital,2019/11/1-2020/10/31; (3) RB was diagnosed by more than two experienced senior specialists on the basis of medical history, physical examination, orbital MR and fundus examination. 2. Inclusion criteria for normal controls: (1) Normal Chinese Han children aged 0-18 years, sex, age ratio matched with the patient group, all samples from healthy children, regular imaging and biochemical testing no obvious organic or psychiatric lesions; (2) All data were assessed as non-RB by the blind method of two senior specialists; 3. Inclusion criteria for the non-RB group of ophthalmic diseases: (1)2019/11/1-2020/10/31 Retinal diseases (retinal artery and vein occlusion, perivenous retinal inflammation, Coats'disease, diabetic and hypertensive retinopathy and central serous chorioretinopathy, macular cystoid edema, macular anterior retinal membrane, retinitis pigmentosa), optic nerve diseases (optic disc dysplasia, optic glioma, optic nerve meningioma, optic nerve atrophy) and non-refractive diseases such as non-RB.
Exclusion criteria
Exclusion criteria: (1) with other systemic diseases; (2) with a recent history of infection; (3) the family history of other diseases was excluded; (4) Without history of other diseases in the eye and no drugs were taken at present.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Protein expression; | — |
Countries
China
Contacts
Public ContactNi Xin
Beijing Children's Hospital, Capital Medical University
Outcome results
None listed