male infertility
Conditions
Interventions
Sponsors
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
22 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the above diagnostic criteria at the same time; (2) Aged 22 to 60 years old; (3) The course of the disease is more than 6 months; (4) Volunteer subjects; (5) Stop other Chinese and Western medicines for treating oligozoospermia; (6) TCM syndrome differentiation is a syndrome of kidney essence deficiency (refer to the relevant standards in the Medical Science of Integrated Traditional Chinese and Western Medicine).
Exclusion criteria
Exclusion criteria: (1) Congenital malformation obstruction, testicular atrophy, varicocele greater than II degrees; (2) Those with obvious genital malformations and reproductive system infections; (3) Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system; (4) Mental illness or a patient with a clear genetic factor; (5) Allergic constitution or allergy to the study drug; (6) Those with a history of active infectious diseases; (7) Those who are engaged in special occupations that have obvious impact on fertility (such as radiation, electric welding, etc.); (8) extremely oligospermia and necrospermia disease patients, positive anti-sperm antibody patients, abnormal of semen liquefaction and another abnormal semen patient; (9) Patients who are considered unsuitable for sexual life or treatment, or who have incomplete data affecting efficacy or safety judgment; (10) The woman has a history of infertility-related diseases, and sexual life is not normal, retrograde ejaculation or no ejaculation, and another sexual dysfunction patient; (11) Those who are taking anti-epileptic diseases and anti-tumor drugs that interfere with sperm production and vitality; (12) Those who have taken spermatogenic drugs in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| semen volume;semen concentration;sperm progressive motility;sperm non-progressive motility;sperm total motility;serum total testosterone; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum estradiol;serum follicle stimulating hormone;serum luteinizing hormone;serum prolactin;partial androgen deficiency in aging male scale;Chinese medicine clinical symptom scale;serum total testosterone; | — |
Countries
China
Contacts
Public ContactYU CHAO
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed