Type 1 Diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)Participants diagnosed with T1DM by endocrinologists and met at least one of the following conditions 1.Obvious diabetes-related metabolic disorder symptoms; 2.Previous diabetic ketosis or ketoacidosis; 3.Tested positive for diabetes autoantibodies such as GAD65, ICA, IA-2/IA-2ß; 4. Had fasting C-peptide level less than 200 pmol/l and stimulated C-peptide less than 500pmol/l; (2)Insulin treatment every day; (3)Residents in Guangdong at least 6 months and have the willingness to follow visitings; (4)Have the willing to participate in the study and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1.Life expectancy less than one year, such as advanced cancer and serious diseases, assessed by researchers; 2. Currently participated/will participate in other potential cross-effected investigational study, assessed by researchers; 3.Other special types of diabetes; 4.Diabetic duration for more than one year and no recurrence of DKA after stopping insulin treatment at least one month; 5.C-peptide level >800pmol/l for more than two times;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting blood glucose;random glucose;c-peptide;blood pressure;lipid;BMI;ACR;opthalmalogic tests; | — |
Countries
China
Contacts
The First Affliated Hospital of USTC