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Clinical effect observation and Mechanism Discussion of low FODMAP diet combined with probiotics in the treatment of irritable bowel syndrome

Clinical effect observation and Mechanism Discussion of low FODMAP diet combined with probiotics in the treatment of irritable bowel syndrome

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026666
Enrollment
Unknown
Registered
2019-10-17
Start date
2016-10-02
Completion date
Unknown
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel disease

Interventions

Group 3:Low FODMAP and Probiotic treatment
Group 1:Low FODMAP diet
Group 2:Probiotic treatment
Group 4:Low FODMAP and Probiotic treatment

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. IBS Rome F. Guidelines - Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders. J Gastrointestinal Liver Dis 2006; 15:307-12): Recurrent abdominal pain or discomfort occurred at least three days a month in the last three months, with the following two or more items: 1. Improvement of postdefecation symptoms; 2. Frequency of defecation accompanied by episodes. Change; 3. Attack accompanied by changes in fecal characteristics (appearance). The symptoms appeared at least 6 months before diagnosis and met the above diagnostic criteria in the last 3 months. All patients were excluded from systemic and local organic diseases by questionnaires, biochemical tests, abdominal ultrasonography, gastroscopy and colonoscopy screening. Patients aged 18-50. Antibiotics or probiotics were discontinued two weeks before the start of the study, and all other IBS therapeutic drugs (such as laxatives and gastrointestinal motility control drugs) were discontinued during the study. Volunteer to join the experiment and sign the informed consent.

Exclusion criteria

Exclusion criteria: History of abdominal surgery, pregnant women, lactating women, patients with other diseases such as diabetes, heart, pulmonary insufficiency, other abdominal organic diseases, patients previously managed by clinical nutritionists.

Design outcomes

Primary

MeasureTime frame
Symptoms Severity Score;

Countries

China

Contacts

Public ContactLiu Ling

West China Hospital, Sichuan University

18980606772@163.com+86 18980606772

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026