Non-muscle invasive bladder cancer
Conditions
Interventions
Gemcitabine group:Intravesical instillation of gemcitabine chemotherapy after bladder tumor surgery
Pseudomonas aeruginosa group:Intravesical instillation of Pseudomonas aeruginosa injection after bladder tumor operation
Sponsors
Lanzhou University Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients and his families who volunteered to participate this study. And Patient is informed and has given written informed consent. 2. 18 years of age and less than 75 years of age, both men and women; 3. Patients undergoing transurethral resection of bladder tumors; 4. Preoperative diagnosis is non-muscle invasive bladder cancer (Ta-T1N0M0), pathological diagnosis of urothelial carcinoma; 5. no previous history of other malignant tumors.
Exclusion criteria
Exclusion criteria: 1. The tumor has been invading the ureter, prostate and urethra; 2. Do not have capable or behavioral capacity is limited; 3. Preoperative routine chest X-ray and pelvic enhancement CT examination revealed that distant metastasis or intraoperative findings of tumor invasive muscle layer. 4. Have other serious diseases, including cardiovascular, respiratory, kidney, or liver diseases, and combine to control patients with poor hypertension and diabetes; 5. Pregnant and lactating women; 6. History of pelvic surgery or lower urinary tract surgery; 7. Preoperative history of chemotherapy; 8. Severe coagulation function abnormal electrolyte balance disorder hypoproteinemia was corrected without obvious improvement; 9. Have narcotic contraindications for the anaphylaxis of narcotic drugs; 10. The researcher considers that there are any other circumstances that are not suitable for participating in the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recurrence rate; | — |
Countries
China
Contacts
Public ContactShang Panfeng
Outcome results
None listed