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Targeted drug development and clinical application based on super bacterial NDM-1 hydrolysis antibiotic mechanism

Targeted drug development and clinical application based on super bacterial NDM-1 hydrolysis antibiotic mechanism

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026638
Enrollment
Unknown
Registered
2019-10-16
Start date
2019-11-05
Completion date
Unknown
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial infections

Interventions

Experimental group versus control group:medicine

Sponsors

the third Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18 to 45 years old; (2) Carbapenem-resistant antibiotics were found by blood susceptibility test; (3) Voluntary treatment of new drugs; (4) Patients who can fully understand the content of informed consent and voluntarily sign written informed consent; (5) Can receive follow-up visits, follow-up examinations and specimens on time.

Exclusion criteria

Exclusion criteria: (1) Those who are taking antibiotics; (2) Patients who are unable to complete a minimum of 60 days of follow-up; (3) Dependent on tube feeding; (4) There are serious diseases that require immediate treatment (such as life-threatening intestinal obstruction, perforation, bleeding); (5) severe immunodeficiency disease; (6) has a history of severe allergies; (7) being diagnosed as a mental disorder or depression; (8) Patients who are unable to complete the study; (9) Other patients considered by the investigator to be unsuitable for inclusion; (10) Food allergies.

Design outcomes

Primary

MeasureTime frame
Blood routine and blood culture;

Countries

China

Contacts

Public ContactQinghua Zhang

the third Affiliated Hospital of Army Medical University

zhangqh1123@163.com+86 13594013576

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026