peripheral neuropathy
Conditions
Interventions
Gold Standard:Neuroelectrophysiological examination
magnetic 
resonance, 
examination
Sponsors
The First Affiliated Hospital of university of Science and Technology of China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Peripheral neuropathy patients and healthy volunteers. Facial neuritis and carpal tunnel syndrome are diagnosed according to the results of neuroelectrophysiology. For including diabetic patients with or without DPN symptoms and signs, the diagnosis of diabetes was based on the revised American diabetes association standard, which includes fasting glucose levels greater than or equal to 126 mg/dl (>=6.1 mmol/L) and postprandial 2h glucose levels greater than or equal to 200 mg/dl (>=11.1 mmol/L).
Exclusion criteria
Exclusion criteria: Multiple neurologic histories due to other etiologies, such as hereditary, alcoholic, metabolic, inflammatory, and toxic factors; Skin damage or swelling can interfere with nerve conduction; And a previous known history of wrist, leg or ankle fractures or surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shear wave elastography;Neuropathy score;Urine alpha 1- microglobulin, Urine beta 2- microglobulin, Urinary transferrin;Percentage of neutrophils, RBC volume distribution width, ratio of platelet to lymphocyte, uric acid, bilirubin, HbA1c, 25-hydroxyvitamin D;Neuromagnetic resonance lesion volume, hyperintense lesion load; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cross sectional Area, Nervous circumference;MiRNA-106a, MiRNA-181C; | — |
Countries
China
Contacts
Public ContactYuanbo Wu
The First Affiliated Hospital of university of Science and Technology of China
Outcome results
None listed