Rectal cancer
Conditions
Interventions
Gold Standard:Surgical and pathological TRG grade (0-3)
Index test:Sequential 
ultrasonography
Sponsors
Departments of Medical Ultrasonics, the Sixth Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Prospective inclusion of patients with colorectal cancer confirmed by pathology and staging of cT3-4,N0-2,M0 (clinical stage II,III stage); 2. Clinical evaluation of potentially resectable patients undergoing complete neoadjuvant chemotherapy and TME surgery; 3. Newly treated patients who have not been treated with antitumor therapy; 4. Patients who were willing to sign informed consents.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot effectively complete transrectal ultrasound evaluation; 2. Patients who withdraw from study due to subjective or objective factors in the course of neoadjuvant chemotherapy; 3. Patients who failed to obtain effective pathology assessment; 4. Patients who were allergic to ultrasound contrast agents or complicated with severe chronic cardiovascular, cerebral, vascular, hepatobiliary and renal diseases, other malignant or immunodeficient diseases,hemorrhagic diseases,pregnant or lactating female patients or other uncontrollable unoperated patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Length, thickness and volume reduction of ERUS2-4/ ERUS1;Ratio of contrast parameters between rectal mass area and normal intestinal wall area; | — |
Countries
China
Contacts
Public ContactGuangjian Liu
the Sixth Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed