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Platelet Dysfunction Detected by Thromboelastography with Platelet Mapping Contributes to Hematoma Expansion and Poor Outcome in Patients with Intracerebral Hemorrhage

Platelet Dysfunction Detected by Thromboelastography with Platelet Mapping Contributes to Hematoma Expansion and Poor Outcome in Patients with Intracerebral Hemorrhage

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026609
Enrollment
Unknown
Registered
2019-10-16
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral Hemorrhage

Interventions

hematoma enlargement group and non-enlargement group:N/A
mRS 3 group:N/A

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged more than 18 years; 2. Patient with intracerebral hemorrhage detected by non-contrast computed tomography (NCCT); 3. Initial CT scanned within 6 hours after symptoms onset, and follow-up CT available within 48 hours after the baseline CT scan; 4. Thromboelastography with platelet mapping obtained on admission.

Exclusion criteria

Exclusion criteria: 1. Traumatic intracranial hemorrhage;intracranial tumor or vascular malformations presumed to be the cause of the hemorrhage;primary intraventricular hemorrhage;hemorrhagic conversion of acute ischemic stroke; 2. Patients who were operated on before the follow-up CT scan; 3. Patients with antiplatelet or anticoagulant treatment.

Design outcomes

Primary

MeasureTime frame
AA inhibition;ADP inhibition;Volume of Hematoma;Prognostic analysis;Is it surgery or epilepsy;

Secondary

MeasureTime frame
Blood routine;Coagulation function;

Countries

China

Contacts

Public ContactQiuguang He

The Second Affiliated Hospital of Chongqing Medical University

598381027@qq.com+86 18716469367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026