Chronic functional constipation
Conditions
Interventions
Constipation group:
Sponsors
Shanxi Bethune Hospital of Shanxi Aademy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. pre-menopausal women, 18-50 years old, about 30 years old is the best; 2. body weight within the normal range, 18.5 < BMI < 23.5; 3. functional constipation Roman IV standards: must comply with the above item 2 or more of the following symptoms: A. defecate taxing over a quarter (25%); B. More than 1/4 (25%) of defecation is dry ball manure or hard manure (type 1-2); C. More than 1/4 (25%) of the defecation feeling; D. More than 1/4 (25%) of defecates have a feeling of anal rectal obstruction/obstruction; E. More than 1/4 (25%) of defecation requires manual assistance; F. spontaneous defecation (SBM) less than 3 times per week.
Exclusion criteria
Exclusion criteria: 1. complicated with diabetes, hypothyroidism, etc.; 2. patients with cancer; 3. patients with Parkinson's disease, mental and psychological diseases, etc.; 4. pregnant or lactating women; 5. history of alcohol and drug abuse; 6. according to the judgment of the researcher, patients with other serious hazards to patient safety or accompanying diseases that affect the completion of the study; 7. those considered unsuitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of bowel movements per week;Defecation effort;Feeling of endless defecation;Intestinal flora;Plasma metabolomics;Stool metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemical test; | — |
Countries
China
Contacts
Public ContactDong Xiushan
Shanxi Bethune Hospital of Shanxi Aademy of Medical Sciences
Outcome results
None listed