Tumor
Conditions
Interventions
experimental group + control group:Synchronous chemoradiotherapy + TPO versus Synchronous chemoradiotherapy
Sponsors
Xiangya Boai Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) All patients were diagnosed as cervical cancer or rectal cancer by pathology, clinical stage was performed according to the staging criteria, and patients with platelet decline with concurrent radiotherapy and chemotherapy according to the CSCO 2019 version of the principle of diagnosis and treatment; (2) diagnostic criteria that met the level 1 decrease of platelet count, that is, all selected All cases showed 75×10^9/L = 70 points, PS score < 2 points; (5) normal liver and kidney function; (6) aged 18-70 years; (7) standardized radiotherapy and chemotherapy for cervical cancer or rectal cancer.
Exclusion criteria
Exclusion criteria: (1) those with bone marrow metastasis; (2) patients with reduced PLT due to non-chemotherapy or radiotherapy and chemotherapy, such as with idiopathic PLT reduction; (3) those with a history of active bleeding; (4) those with a history of thromboembolism; (5) patients with severe uncontrollable Infection; (6) poor patient compliance; (7) pregnancy or other patients with untreated cancer; (8) with contraindications for radiotherapy and chemotherapy; (9) serious medical diseases; (10) the investigator believes that continuing the trial does not meet scientific or ethical principles.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet; | — |
Countries
China
Contacts
Public ContactLong Bin
Xiangya Boai Rehabilitation Hospital
Outcome results
None listed