Lumbar disease
Conditions
Interventions
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient was clearly diagnosed as lumbar disc herniation, lumbar spinal stenosis or lumbar spondylolisthesis, and received regular conservative treatment for 3 months, with no significant relief of symptoms.Patients were proposed to undergo posterior lumbar decompression and fusion. 2. Aged 18-80 years. 3. ASA I- III. 4. Patients volunteered to participate in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with allergy to TXA; 2. patients with previous history of coagulation dysfunction, thrombotic disease, or preoperative diagnosis of deep vein thrombosis by venous ultrasonography or angiography; 3. patients with severe damage to vital organs and difficult to cooperate with orthopedic treatment; 4. PLT 160/90mmhg); 7. ASA)> III 8. BMI>30kg/m2; 9. severe osteoporosis; 10. pregnant women or patients with severe mental illness; 11. take nsaids within one week before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| length of operation;intraoperative blood loss;Postoperative drainage;Volumes of infused blood;Complications and adverse events; | — |
Countries
China
Contacts
Public ContactFeng Shuo
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed