Skip to content

Multi-center Study of Application of LungClearTM (hTERT mRNA Test from Sputum) in Screening for Lung Cancer

Multi-center Study of Application of LungClearTM (hTERT mRNA Test from Sputum) in Screening for Lung Cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026553
Enrollment
Unknown
Registered
2019-10-13
Start date
2019-10-19
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Gold Standard:pathological diagnosis
Index test:hTERT

Sponsors

Beijing Chest Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1) Adults aged 18-74 years; 2) pulmonary nodules after imaging screening, which are suspected to be lung cancer lesions; 3) plan to receive surgery or needle biopsy to confirm the pathological diagnosis; 4) sputum can be coughed routinely or sputum can be coughed under the guidance of medical personnel, or bronchial examination can be conducted to obtain bronchial lavage fluid.

Exclusion criteria

Exclusion criteria: 1) imaging examination determined pulmonary nodules as metastatic nodules; 2) have a clear history of cancer or are currently receiving any form of anti-tumor therapy; 3) other pulmonary diseases (active tuberculosis, asthma, idiopathic pulmonary interstitial fibrosis); 4) pregnancy (pregnancy is defined as the state of a woman from pregnancy to termination confirmed by a positive hCG laboratory test); 5) imaging screening positive suspected lung cancer but refused to carry out histological diagnosis; 6) mental illness; 7) informed consent cannot be signed.

Design outcomes

Primary

MeasureTime frame
SEN, SPE, ACC, AUC of ROC;LDCT;

Countries

China

Contacts

Public ContactZhi Xiuyi

Beijing Chest Hospital, Capital Medical University

13901297065@163.com+86 13901297065

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026