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Application of Transcranial Magnetic Stimulation in Adult Amblyopia Treatment and Related Mechanisms

Application of Transcranial Magnetic Stimulation in Adult Amblyopia Treatment and Related Mechanisms

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026548
Enrollment
Unknown
Registered
2019-10-13
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

amblyopia

Interventions

cTBS:cTBS Low frequency stimulation of the healthy visual cortex
iTBS:iTBS High frequency stimulation of the affected visual cortex
False stimulation:no stimulation

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for amblyopia; 2. Monocular amblyopia; 3. Strabismus amblyopia,Anisometropic amblyopia; 4. Aged 18-45 years; 5. Willing to participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. A history of epilepsy, a history of idiopathic epilepsy in first-degree relatives, and the use of epileptic drugs; 2. Patients with diabetes or serious cardiovascular disease, cerebrovascular disease, liver disease, kidney disease and mental disorders; 3. Severe cognitive and communication impairment and inability to cooperate; 4. Wear a pacemaker, have a metal or electronic implant in the skull, or have a skull defect; 5. Direct injury to the stimulus area; 6. There are implants such as heart pacemakers, artificial metal heart valves, insulin pumps, medication pumps, aneurysm clips (except for non-paramagnetic devices such as titanium alloys); 7. Severe hyperthermia; 8. claustrophobic; 9. Functional magnetic resonance imaging examines uncooperative patients; 10. Patients who had received any form of amblyopia treatment within the last 3 months; 11. Amblyopia with nystagmus; 12. Amblyopia with eye movement disorder; 13. Amblyopia with ocular trauma; 14. Amblyopia with cataract and/or vitreous surgery; 15. Patients with binocular amblyopia.

Design outcomes

Primary

MeasureTime frame
visual acuity;contrast sensitivity;

Countries

China

Contacts

Public ContactLiuhu

The first affiliated hospital of nanjing medical university

liuhu@njmu.edu.cn+86 13952091066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026