Acute myocardial infarction
Conditions
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patients with acute myocardial infarction within 12 hours, underwent emergency PCI, or underwent PCI after emergency thrombolytic therapy; 2. The patients meet the syndrome differentiation standard of TCM with Deficient Qi and Yin combined blood stasis; 3. Aged 18 to 75 years, both men and women; 4. Sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Stable angina or unstable angina; 2. Acute myocardial infarction with heart failure, Killip classification II, III or IV; 3. Acute myocardial infarction with severe complications, such as cardiogenic shock(conventional treatment cannot correct), or mechanical complication; 4. Severe arrhythmia, such as Rapid atrial fibrillation, ventricular tachycardia, high atrioventricular block, etc. 5. Chronic heart failure or old myocardial infarction in the past medical history; 6. Combined with other diseases, such as cardiomyopathy, rheumatic heart disease, severe valvular heart disease, cardiac tamponade, hypertension emergency, pulmonary arterial hypertension, acute paroxysmal asthma /COPD, severe infection , and so on; 7. Patients with severe liver and kidney function impairment (ALT >3 times the upper limit of normal reference value, or Cr >= 3mg/dL or eGFR<= 60ml/min1.73m2); and with severe primary diseases such as endocrine or hematopoietic system; and with mental diseases; 8. Patients with malignant tumor; 9. Allergic constitution or allergy to multiple drug or food, allergy to known components of the study drugs; 10. Cannot take care of themselves and cannot receive oral drug; 11. Participated in other drug clinical trials within 3 month; 12. Suspecting or ensuring with a history of substance abuse alcohol or drug abuse; 13. Pregnant or lactating women, or planned pregnancy; 14. Patients with cerebral vascular accidents, major surgery and trauma recently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Incidence of Heart failure; | — |
Secondary
| Measure | Time frame |
|---|---|
| type B natriuretic peptide(BNP);Echocardiography;6-min walk test (6-MWT);hypersensitive C reactive protein;traditional Chinese medicine(TCM) syndrome score;Minnesota questionnaire;Major adverse cardiovascular events (MACEs); | — |
Countries
China
Contacts
Public ContactWu Wei
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed