Clinical study for the changes of mucosal microbial characteristics during the development of esophageal cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900026528

Enrollment

Unknown

Registered

2019-10-13

Start date

2019-07-22

Completion date

Unknown

Last updated

2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

Normal esophagus group

esophagitis group

esophageal early cancer group

advanced esophageal cancer group:no

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18-75 years old; 2) Endoscopic and pathological examinations suggest normal esophagus, esophagitis, early esophageal cancer, and advanced esophageal cancer; 3) Voluntarily accept and abide by this protocol, receive review and follow-up on time, informed consent.

Exclusion criteria

Exclusion criteria: 1) There are antibiotics in recent 2 months or a history of PPI or non-steroidal anti-inflammatory drugs in the past 2 weeks; 2) Taken probiotics in the past week; 3) Taken proton pump inhibitor in the past 2 weeks; 4) Receive preoperative chemotherapy or radiation therapy; 5) Patients with severe cardiovascular and cerebrovascular diseases and other organic diseases cannot tolerate endoscopic surgery; 6) pregnant and lactating women; 7) With psychosomatic diseases and unable to cooperate with the tester.

Design outcomes

Primary

Measure	Time frame
Mucosal microbial composition;	—

Countries

China

Contacts

Public ContactShiming Yang

Xinqiao Hospital of Army Military University

shimingyang@yahoo.com+86 13228686589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026