Clinical study for the changes of mucosal microbial characteristics during the development of gastric cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900026526

Enrollment

Unknown

Registered

2019-10-13

Start date

2019-07-22

Completion date

Unknown

Last updated

2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Normal stomach group, Chronic gastritis group, Atrophic gastritis group, Early gastric cancer group, Advanced gastric cancer group:no

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years old; 2. Gastroscope and pathological examination suggest normal gastric mucosa and chronic gastritis, atrophic gastritis, gastric cancer (early and advanced) patients; 3. Voluntarily accept and abide by this protocol, and receive review and follow-up on time, informed consent.

Exclusion criteria

Exclusion criteria: 1. There have been antibiotics in recent 2 months or a history of PPI or non-steroidal anti-inflammatory drugs in the past 2 weeks; 2. taken proton pump inhibitors in the past 2 weeks; 3. Have received preoperative chemotherapy or radiation therapy; 4. Those who have other diseases such as cardiovascular and cerebrovascular diseases and who are not suitable for endoscopy; 5. Pregnancy and lactation; 6. Suffering from psychosomatic diseases, unable to cooperate with the tester.

Design outcomes

Primary

Measure	Time frame
Gastric mucosal microbe composition;Oropharyngeal microbe composition;	—

Secondary

Measure	Time frame
Histopathological index;Hp infection;	—

Countries

China

Contacts

Public ContactShiming Yang

Xinqiao Hospital of Army Military University

shimingyang@yahoo.com+86 13228686589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026