A prospective randomized controlled trial for effects of prophylactic clamping of the chest tube on the incidence of extubation-related complications after lung surgery

A prospective randomized controlled trial for effects of prophylactic clamping of closed thoracic drainage tube on the incidence of extubation-related complications after VATS pulmonary lobectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026522

Enrollment

Unknown

Registered

2019-10-13

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary diseases required for surgery

Interventions

Experimental Group:24-hour clamping before extubation

Control Group:no clamping before extubation

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with unilateral lobectomy; 2. aged 18 to 75 years; 3. Karnofsky's score >=80; 4. Subjects who can understand, follow the protocol, and sign for informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with pulmonary bullae or patients with clinical history of spontaneous pneumothorax; 2. Patients with severe emphysema; 3. Patients who received chemotherapy and/or radiotherapy before surgery; 4. Patients with poor liver or kidney reserve, severe cirrhosis or abnormal coagulation indicators; 5. Patients with poor compliances, that can not complete follow-up according to protocol.

Design outcomes

Primary

Measure	Time frame
Extubation-related complications;	—

Secondary

Measure	Time frame
Postoperative hospital stay;Re-admission rate within 30 days after discharge;Postoperative hospitalization expenditure;Re-intubation rate after extubation;	—

Countries

China

Contacts

Public ContactYang Yunhai/Chen Tianxiang

Shanghai Chest Hospital

docyyh@163.com+86 17602108896/13918789159

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026