stroke
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years old; 2. The first onset of the disease lasted more than 3 weeks; 3. Unilateral stroke, confirmed by CT or MRI; 4. Patients have poststroke spasticity with a modified Ashworth scale (MAS) score between 1+ and 3; 5. Having good communication ability and absence of cognitive impairment; 6. Voluntary signing of informed consent and willingness to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with musculoskeletal or other neurological diseases,other than stroke; 2. Cerebellar or brainstem stroke; 3. Used antispasticity drugs or had a local injection of botulinum toxin A within 3 months before enrollment; 4. Had contraindications to rTMS (e.g. with a history of epilepsy or migraine; with cardiac pacemakers, cochlear implants, metal implants in the skull and increased intracranial pressure; pregnancy); 5. Complicated with severe systemic diseases, and unstable vital signs; 6. With peripheral nerve injury, such as diabetic neuropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Ashworth scale;modified Tardieu scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compound muscle action potentials,Fwave and Hoffmann reflex;Shear Wave Ultrasound Elastography;motor evoked potential;Modified Rivermead Mobility Index;Barthel index;National Institutes of Health Stroke Scale; | — |
Countries
China
Contacts
Public ContactQiang Gao
West China Hospital, Sichuan University
Outcome results
None listed