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Effect of Nasal Application of Dexmedetomidine on the Incidence of Post Desflurane Anaesthesia Agitation in Children

Effect of Nasal Application of Dexmedetomidine on the Incidence of Post Desflurane Anaesthesia Agitation in Children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026509
Enrollment
Unknown
Registered
2019-10-13
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chidren undergoing desflurane-based general anaesthesia

Interventions

Group 1:1ug/kg dexmedetomidine given by intravenous injection
Group 2:2ug/kg in 0.6ml dexmedetomidine given by nasal drop
Group 3:2ug/kg in 0.6ml dexmedetomidine given by nasal spray via a atomizer

Sponsors

West China Second Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 8 Years

Inclusion criteria

Inclusion criteria: 1. Consent form from parents; 2. Children with inguinal hernia aged from 1-8 years undergoing surgical repair with desflurane-based general anesthesia; 3. Children in good general conditiong without major co-morbility.

Exclusion criteria

Exclusion criteria: 1. History of asthma; 2. With other congenital diseases; 3. Coagulation disorder; 4. Contradicted to general anesthesia.

Design outcomes

Primary

MeasureTime frame
Agitation Score (PAED Score) during post-anaestheisa recovery period;—

Countries

China

Contacts

Public ContactHan Huang

West China Second Hospital, Sichuan University

han.huang@scu.edu.cn+86 18180609889

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026