A randomized controlled tiral for the effect of preoperative Vitamin D supplementation on the incidence of Post Operative Cognitive Dysfunction in old patients after surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026494

Enrollment

Unknown

Registered

2019-10-12

Start date

2019-10-14

Completion date

Unknown

Last updated

2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

Experimental group:Vitmin D3

Control group:D-Cal calcium

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients of elective abdominal surgery in general anesthesia; 2. Expected surgery duration more than 2 hours; 3. Aged >=65 years; 4. vitamin D insufficiency.

Exclusion criteria

Exclusion criteria: 1. refused to participate; 2. vitamin D contraindication patients: hypercholesterolemia, hyperphosphatemia, chronic renal insufficiency (need dialysis patients), vitamin D allergy; 3. ASA>=4.

Design outcomes

Primary

Measure	Time frame
Incidence of cognitive impairment on day 5 after operation;	—

Secondary

Measure	Time frame
incidence of emergence delirium and postoperative delirium within 5 days;postoperative 30-day compliations and mortality;postoperative hospital length of stay;expense during hospital stay;postoperative 30-day mortality;Questionnaire survey on quality of life 3 months after operation;Telephone Interview for Cognitive Status;	—

Countries

China

Contacts

Public ContactMu Dongliang

mudongliang@iCloud.com+86 13810702725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026