Bronchopulmonary Dysplasia
Conditions
Interventions
Experimental Group:Vibration mesh atomization inhaled glucocorticoids combined invasive/non-invasive ventilation
Control Group:invasive / non-invasive auxiliary ventilation
Sponsors
Guangdong Women and Children Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Fetal age <=30 weeks and birth weight <=1500g; 2. Aged <=12 hours after birth; 3. Those who meet the RDS Diagnostic Standards for Practical Neonatology (4th edition); 4. With the child's guardian's informed consent
Exclusion criteria
Exclusion criteria: 1. Congenital malformations of the respiratory system, complex congenital heart disease, severe intrauterine infection, severe instability of the circulatory system, congenital genetic metabolic diseases and chromosomal diseases; 2. Family members refuse to participate; 3. Those who fail to complete the study and cannot provide complete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood gas analysis;Ventilator parameters;Vital signs;Treatment failure; | — |
Secondary
| Measure | Time frame |
|---|---|
| ventilation time;Bronchopulmonary dysplasia;Retinopathy of prematurity;Necrotizing enterocolitis;Air leak;intraventricular hemorrhage ;Number of deaths;Patent ductus arteriosus; | — |
Countries
China
Contacts
Public ContactJia Chen
Guangdong Women and Children Hospital
Outcome results
None listed