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Biological function and clinical evaluation of probiotic lactic acid bacteria for prevention and treatment of metabolic diseases

Biological function and clinical evaluation of probiotic lactic acid bacteria for prevention and treatment of metabolic diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026469
Enrollment
Unknown
Registered
2019-10-11
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia

Interventions

control group:Placebo

Sponsors

Inner Mongolia people's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Male or female, aged 18-70 years; 2. BMI (Body Mass Indx) between 24 kg/m2-30kg/m2; 3. Male waist circumference >=90cm, female waist circumference >=85 cm; 4. Agreed to participate in the study and signed written informed consent; 5. newly discovered or previously hyperlipidemia patients.

Exclusion criteria

Exclusion criteria: 1. Pregnant and nursing women; 2. Liver dysfunction: alanine aminotransferase and aspartate aminotransferase = normal high limit of 2 times or more; 3. Renal dysfunction: glomerular filtration Over-rate =90ml/min/1.72m2; 4.Hypertension, use more than 2 kinds of antihypertensive drugs and the blood pressure is still higher than 160/100mmHg; 5. Cardiac dysfunction; 6. Suffer from anemia or other blood diseases; 7.Diabetes patient; 8. antibiotics were used in the previous month; 9. With chronic gastrointestinal disease history; 10. With other complications; 11. used lipid-lowering drugs.

Design outcomes

Primary

MeasureTime frame
bacterial diversity;immune index;metabonomics;Metagenomics;Blood lipid;

Countries

China

Contacts

Public ContactGuo Ruifang

Inner Mongolia people's Hospital

grf_6872@163.com+86 18047192249

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026