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Ratio of asprosin/leptin in peripheral blood predicts a long-term maintenance of weight loss after an energy restriction treatment

Ratio of asprosin/leptin in peripheral blood predicts a long-term maintenance of weight loss after an energy restriction treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026463
Enrollment
Unknown
Registered
2019-10-11
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obese

Interventions

Case series:energy restiction treatment

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years old; 2. BMI 28 to 40 kg/m2.

Exclusion criteria

Exclusion criteria: 1. secondary obese patients (such as Cushing syndrome); 2. people diagnosed with type 2 diabetes or baseline fasting blood glucose >=7.0mmol/l, HbA1c>=6.5%; 3. pregnant or lactating women; 4. people with infections, malignant tumors, severe liver dysfunction (hepatic enzymes greater than 3 times the upper limit of normal), abnormal renal function (the serum creatinine is 1.5 times higher than the upper limit of normal and / or a large amount of proteinuria), severe heart disease or uncontrolled thyroid function; 5. patients with drug or alcohol addiction or have uncontrollable mental illness; 6. cognitive impairment or immature intelligence, other circumstances in which informed consent cannot be given; 7. Drugs that affect weight (including GLP-1, metformin, orlistat, etc.) have been used; 8. people who lost more than 3kg in the first three months of enrollment.

Design outcomes

Primary

MeasureTime frame
weight;height;waist circumference;hipline;body fat content;blood pressure;leptin;asprosin;

Countries

China

Contacts

Public ContactLi Jialin

Ningbo First Hospital

lijialin@sina.com+86 13780008400

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026