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Efficacy of Sucralfate Suspensoid Gel in the treatment of artificial ulcer after esophageal ESD surgery: a multicenter randomized controlled trial

Efficacy of Sucralfate Suspensoid Gel in the treatment of artificial ulcer after esophageal ESD surgery: a multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026441
Enrollment
Unknown
Registered
2019-10-10
Start date
2019-11-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal artificial ulcer

Interventions

Experience group:After operation, the wound was covered with sucralfate gel.
control group:Sucralfate gel was not applied to cover the wound after surgery

Sponsors

The Second Affiliated Hospital of Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years and < 70 years; 2. In-patient cases, men and women are not limited; 3. Patients with esophageal mucosal lesions requiring ESD treatment (including early esophageal cancer, lesion range less than 2/3 weeks); 4. Cases that conform to the indications of ESD operation and complete ESD operation; 5. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women, or women with family planning during the study period; 2. Cases with severe cardiovascular diseases, respiratory, blood, liver and kidney, hemorrhagic diseases and other poor physical fitness; 3. Patients with psychiatric disorders; 4. Those who take drugs affecting bleeding and coagulation function (such as non-steroidal anti-inflammatory drugs, adrenocortical steroids, anticoagulants) at the same time; 5. Patients allergic to drugs in our institute; 6. Participated in other drug research in the first three months. 7. Poor compliance in comprehensive judgment. 8. After ESD, the wounds were clamped; after ESD, the perforated wounds were not included in the group.

Design outcomes

Primary

MeasureTime frame
Ulcer healing rate;

Secondary

MeasureTime frame
Delayed hemorrhage rate;Incidence of stenosis;Surgical rate;Hospitalization expenses;Length of stay;

Countries

China

Contacts

Public ContactYang shi ming

The Second Affiliated Hospital of Military Medical University

shimingyagn@yahoo.com+86 13228686589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026