Breast Cancer
Conditions
Interventions
Experimental group:Docetaxel
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pathologically diagnosed malignant tumors and patients who were assessed by the attending physician with docetaxel-containing chemotherapy regimen; 2. Aged not less than 20 years, not more than 80 years 3. Not less than 3 weeks from the last chemotherapy; 4. Adequate renal function (creatinine = 2.0 *10^9/L), white blood cells (>= 4.0 *10^9/L), platelets (>= 100 *10^9/L); 5. Adequate physical condition (PS score 0-2), and the expected survival time are not less than 3 months.
Exclusion criteria
Exclusion criteria: 1. Aged above 80 years; 2. Other malignant tumors; 3. Pregnancy, or lactation, or mental disorders requiring intervention; 4. Severe heart disease, or uncontrollable infections; 5. A history of radiotherapy within four weeks; 6. Uncontrollable hypertension, diabetes; 7. And local or systemic inflammation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The peak concentration;Steady-state concentration;The type of CYP3A5* 3, CYP1B1* 3, ABCB1 1236C > T, ABCB1 2677G > T/A, ABCB1 3435C > T genes; | — |
Countries
China
Contacts
Public ContactGuan Yuyao
Shandong Provincial Third Hospital
Outcome results
None listed