Carotid atherosclerosis
Conditions
Interventions
Group 1:Received a complete EECP course (cuff pressures of 300mmHg ) based on the standard drug treatment
Group 2:Received a complete EECP course (cuff pressures of 70mmHg) based on the standard drug treatment
Sponsors
The Eighth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
21 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 21-75 years. 2. Patients with Carotid plaque (MRI type: III-VIII), no surgical indications. 3. Can accept and cooperate with more than half a year of follow-up. 4. Informed consent form approved by the Ethics Committee.
Exclusion criteria
Exclusion criteria: 1. Significant aortic regurgitation, aortic aneurysm, and dissection aneurysm; 2. Coronary artery spasm or severe coronary aneurysm; 3. Symptomatic congestive heart failure; 4. Heart valve disease, congenital heart disease, cardiomyopathy; 5. Cerebral hemorrhage within half a year, hemorrhagic disease or clear bleeding tendency; 6. Lower extremity infection, phlebitis, severe varicose veins, deep vein thrombosis; 7. Progressive malignancy or serious disease with poor prognosis; 8. Systolic blood pressure >= 180mmHg, or diastolic blood pressure >= 110mmHg when randomly grouped; 9. Severe arrhythmia affecting EECP therapy; 10. Implanted cardiac pacemaker; 11. Claustrophobia, epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fiber cap integrity and thickness;Volume percentage change of carotid plaque; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ipsilateral cerebral infarction;Flow mediated dilatation;Ankle brachial index;Carotid plaque morphology and acoustic changes;Blood lipid;Serum inflammatory markers; | — |
Countries
China
Contacts
Public ContactGuifu Wu
The Eighth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed