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The effect of amiodarone and esmolol on prevention of reperfusion ventricular fibrillation in open heart surgery

The effect of amiodarone and esmolol on prevention of reperfusion ventricular fibrillation in open heart surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026429
Enrollment
Unknown
Registered
2019-10-09
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reperfusion ventricular fibrillation

Interventions

experimental group:amiodarone
control group:esmolol

Sponsors

The First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Subjects, American Society of Anesthesiologists grade II or III, ready for elective heart surgery with cardiopulmonary bypass (CPB). 2. Subjects, understand and voluntarily endorse informed consent.

Exclusion criteria

Exclusion criteria: 1. Subjects, a contraindication or hypersensitivity to taking amiodarone and esmolol. 2. A History of bronchial asthma. 3. A history of open heart surgery. 4. Significant arrhythmias, 5. Liver dysfunction, kidney dysfunction, endocrine disease, any other diseases or pathological conditions that can interfere with the experimental results.

Design outcomes

Primary

MeasureTime frame
defibrillation;—

Secondary

MeasureTime frame
mean arterial pressure;heart rate;—

Countries

China

Contacts

Public ContactTian Ayong

The First Affiliated Hospital of China Medical University

tay0626@126.com+86 13940182455

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026