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Non-randomized controlled clinical study of STS combined with low-dose interleukin-2 in the treatment of moderate to severe atopic dermatitis

Non-randomized controlled clinical study of STS combined with low-dose interleukin-2 in the treatment of moderate to severe atopic dermatitis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026411
Enrollment
Unknown
Registered
2019-10-08
Start date
2018-07-01
Completion date
Unknown
Last updated
2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis

Interventions

Control group:treatment with antihistamine therapy and topical steroid
Experimental group:treatment with antihistamine therapy and topical steroid combined use of STS and cytokine X

Sponsors

Dermatology Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 12-65 years old; 2. Meet the Hanfin and Rajka diagnostic criteria of atopic dermatitis; 3. Total SCORAD 25 scores or higher; 4. The investigator's global assessment 3 scores or higher; 5. The chronic atopic dermatitis present for 3 years or longer; 6. The atopic dermatitis not adequately controlled by topical treatments; 7. Vital signs stable; 8. The subject has signed the written informed consent of the study and compliant this clinical research plan.

Exclusion criteria

Exclusion criteria: 1. Pregnant woman or breast-feeding woman; 2. Abnormal immune function, abnormal kidney and liver function, serious cardiovascular disease, malignant tumor, acute and chronic infection, and any other diseases which may interference test results; 3. Bad control of blood glucose, blood pressure and other disease; 4. Antibiotics, hormones and immunosuppressants were used in the past 1 month; 5. People with mental illness or who cannot cooperate in treatment.

Design outcomes

Primary

MeasureTime frame
the SCORAD Index;The investigator's global assessment;EASI 50;EASI 75;

Secondary

MeasureTime frame
numerical rating scale for pruritus;

Countries

China

Contacts

Public ContactLiang Yunsheng

Dermatology Hospital of Southern Medical University

yunshengliang@aliyun.com+86 15973189908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026