Oral soft tissue defect
Conditions
Interventions
experimental group: Implantation of oral protective film produced by Beijing Bohuizhen Biotechnology Co., Ltd.
control group:Implantation of oral repair film produced by Yantai Haiao
Sponsors
Wuhan University Stomatological Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 75 years old and be able to act autonomously; (2) To select a 1.5 to 20 cm2 area be an observation wound area; (3) patients with oral soft tissue defects caused by various causes need tissue transplantation to cover the wound; (4) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) With systemic and local contraindications; (2) Patients who are not tolerant of the procedure; (3) Pregnant or breast-feeding women; (4) an allergic constitution group, in particular to a pig source material; (5) The fasting blood glucose was 8.8 mmol/ L or 2 hours after the meal, the blood glucose was 11.1 mmol/ L. (6) The liver and renal function were abnormal (TB, ALT, AST, ALP was 1.5 times higher than the upper limit and Cr was above normal); (7) Patients who received radiotherapy within 4 weeks before screening; (8) With an acute infection in the defect area; (9) Other clinical trials have been attended within 3 months; (10) Other cases considered unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 12 ±2 days after operation, the success rate of wound repair was removed.; | — |
Countries
China
Contacts
Public ContactWang Xiaona
Beijing Biosis Healing Biological Technology Co., Ltd
Outcome results
None listed