postoperative delirium
Conditions
Interventions
EEG-guided Group:Anesthesiologists adjust the depth of anesthesia by observing EEG devices
Usual Care Group:Anesthesiologists adjust the depth of anesthesia depending on their own experience
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 65 years and above, ASA grade III and below; 2. Joint replacement surgery under general anesthesia; 3. MoCA score >= 26.
Exclusion criteria
Exclusion criteria: 1. There is delirium before operation; 2. History of neuropsychiatric disease,including: epilepsy, Parkinson's syndrome,schizophrenia, craniocerebral injury, intracranial neoplasms/metastases, intracranial inflammation, stroke; 3. Drug or alcohol abuse; 4. Hearing or visual impairment; 5. Other concomitant diseases: renal failure, liver failure, heart failure, respiratory diseases(COPD), poorly controlled hypertension, severe obesity (BMI >= 40 kg/m2).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| delirium incidence on postoperative days 1 through 5;the average value of spectral egde frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| the dosage of the anesthetics; | — |
Countries
China
Contacts
Public ContactYing Xiao
The First Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed