Osteonecrisis of the femoral head
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-55 years, male or female, non-traumatic femoral head necrosis; (2) X-ray of the hip joint is showing C1 type femoral head necrosis; (3) Patients with ARCO stage of ONFH who are stage II with significant pain and patients with stage IIIA with pain or limited mobility; (4) The affected femoral head did not collapse or collapsed less than 4mm, the joint space was not significantly narrow, and the head-to-head matching relationship was good; (5) The patient agrees to participate in the trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with other diseases that affect the progression of ONFH (such as major diseases of heart, lung, liver and kidney system, nephrotic syndrome, systemic lupus erythematosus, etc. still need to take hormones) and are in active period; (2) Subjects suffering from hip or surrounding fractures, infections, tumors, etc. during the trial; (3) Subjects with serious adverse reactions during the test; (4) The investigator believes that it is not appropriate to continue to participate in the subjects of this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Harris score;Collapse rate;Later sidewall thickness;Bone marrow edema;Femoral head cartilage thickness;Vascular evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Hip mobility;SF-12 score;Blood analysis;Coagulation four;Bone metabolism index; | — |
Countries
China
Contacts
Public ContactWei He
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed