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Mechanism of Shugan Jieyu Capsule for Improving Cognitive Function in Altered Dynamics of Brain of Post-Stroke Depression Patients

Mechanism of Shugan Jieyu Capsule for Improving Cognitive Function in Altered Dynamics of Brain of Post-Stroke Depression Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026358
Enrollment
Unknown
Registered
2019-10-02
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post stroke depression

Interventions

patients with poststroke depression group:Shugan Jieyu Capsule
healthy control group:N/A

Sponsors

The First Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. The first hemorrhagic or ischemic stroke diagnosed by CT or MRI; 2. The incidence of depression is closely related to stroke, which occurs 1 week to 3 months after stroke. 3. Mild to moderate depression, hamd-24 8 < score < 24; 4. Aged 50-70 years, right-handedness, han nationality, gender not limited; 5. Clear consciousness.

Exclusion criteria

Exclusion criteria: 1. Patients with dementia, epilepsy, traumatic brain injury and other brain diseases before stroke or patients with recurrent stroke; 2. Aphasia, apraxia, visual or auditory impairment, unable to complete psychological measurement; 3. Complicated with serious organic diseases (serious abnormalities of heart, lung, liver and renal function, serious infection, chronic inflammatory diseases, tumors and blood diseases); 4. During the first 2 months of the study, patients were given drugs that affect mental activity, or any antidepressant drugs, or received electroconvulsive therapy or were receiving systematic psychotherapy; 5. Other mental disorders and substance abusers.

Design outcomes

Primary

MeasureTime frame
Mental scale;Functional magnetic resonance;

Countries

China

Contacts

Public ContactXu Yong

The First Hospital of Shanxi Medical University

xuyongsmu@vip.163.com+86 18234016125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026