Clinical study for accurate exercise and flora intervention in the treatment of recurrent abortion complicated with metabolic syndrome

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026336

Enrollment

Unknown

Registered

2019-09-30

Start date

2019-09-23

Completion date

Unknown

Last updated

2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent spontaneous abortion complicated with metabolic syndrome

Interventions

1:Transportation intervention

2:Flora intervention

3:Exercise and bacterial population intervention

4:no intervention

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) patients in accordance with the RSA diagnostic criteria and combined with MS; (2) patients with a course of at least 6 months; (3) women with an insufficient amount of exercise in the range of 20 to 40 years old; (4) patients with stable disease control in one year without an acute metabolic disorder; (5) the subject is willing to adhere to regular exercise and flora intervention treatment; (6) subject informed consent, and sign the relevant documents. The process of obtaining the informed consent form shall be in accordance with the requirements of the gcp.

Exclusion criteria

Exclusion criteria: (1) Patients with severe myocardial ischemia, proliferative retinopathy, renal insufficiency, malignant hypertension, unstable blood glucose control, and the like; (2) Replacing oral hypoglycemic agents, reducing drugs or regulating blood lipid drugs over the last two months; (3) The body weight was changed by 5% in the past two months; the blood myography was 2.26 mg/ dL (200 µmol/ L); the proteinuria was more than 1 g/ d; the blood pressure was more than 160/95 mm Hg; (4) Other ECG, routine, ophthalmological, blood pressure, etc. were examined for movement contraindication; (5) The abnormal structure of the uterus: such as the uterine malformation; (6) The administration of antibiotics in the last three months; (7) The habit of regulating the intestinal products such as probiotics and biotics.

Design outcomes

Primary

Measure	Time frame
sugar tolerance;insulin;blood fat;glycosylated hemoglobin;interleukin;tumor necrosis factor;Hemorheology;C reactive protein;Analysis of intestinal flora diversity based on 16s rDNA;	—

Countries

China

Contacts

Public ContactLiu Qingzhi

Department of Reproductive and Immunologic, Shenzhen Maternity and Child Healthcare Hospital

liuqingzhi1002@126.com+86 13825266991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026