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Study for correlation between aristolochic acid-related preparations and tumorigenesis

Study for correlation between aristolochic acid-related preparations and tumorigenesis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900026318
Enrollment
Unknown
Registered
2019-09-29
Start date
2019-10-15
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aristolochic acid nephropathy and its associated tumor

Interventions

Case series:Nil

Sponsors

Fifth Medical Centre, General Hospital of Chinese PLA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. the presence of a defnite history of taking AA-containing medications prior to disease onset; 2. the presence of obvious tubular dysfunction, with or without diminished GFR as a diagnostic criterion; 3. Any age and gender patients with aristolochic acid nephropathy who has been followed for more than 1 year.

Exclusion criteria

Exclusion criteria: 1. Recent or long-term ingestion of antibiotics, nonsteroidal anti- in?ammatory drugs, diuretics or Chinese traditional medicines containing minerals or metals; 2. Evidence of other glomerular or tubulointerstitial diseases caused by infectious or immune diseases; 3. Patients with aristolochic acid nephropathy who were followed up for less than 1 year.

Design outcomes

Primary

MeasureTime frame
Death;Cancer;Renal failure;

Countries

China

Contacts

Public ContactBai Zhaofang

Fifth Medical Centre, General Hospital of Chinese PLA

baizf2008@126.com+86 13488670266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026