Effect of general anesthesia and general anesthesia combined with peripheral nerve block on the prognosis of hip replacement patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026307

Enrollment

Unknown

Registered

2019-09-29

Start date

2020-01-01

Completion date

Unknown

Last updated

2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Group G:general anesthesia

Group G+N:general anesthesia combined with peripheral nerve block

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=65 years; 2. Total hip replacement under general anesthesia or general anesthesia combined with peripheral nerve block anesthesia; 3. Total hip replacement for the first time.

Exclusion criteria

Exclusion criteria: 1. refusal to participate; 2. Patients with MMSE score less than 26 points; 3. Brain injury or chronic brain disease with sequelae; 4. preoperative ASA grade >=IV; 5. Patients with hearing and/or visual impairment; 6. preoperative NYHA classification III or higher; 7. Patients with severe renal insufficiency (requiring dialysis); 8. Severe liver dysfunction (child-pugh score >=10).

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium;	—

Secondary

Measure	Time frame
IL-1 beta and CRP levels at each time point;Pain score;Subjective sleep quality;length of stay in hospital after surgery;Incidence of non-delirium complications after surgery;All-cause 30-day mortality after surgery;The incidence of transferring to ICU ;	—

Countries

China

Contacts

Public ContactZongwang Zhang

Liaocheng People's Hospital

zwzhang68@sina.com+86 13346256809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026