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The recovery mechanism of rTMS on non-fluent aphasia after stroke: an investigation by rs-fMRI

The recovery mechanism of rTMS on non-fluent aphasia after stroke: an investigation by rs-fMRI

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026305
Enrollment
Unknown
Registered
2019-09-29
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

High brain structure retention group 1:low frequency true stimulation
high brain structure retention group 2:high frequency true stimulation
high brain structure retention group 3:pseudo-stimulation
low brain structure retention group 1:low frequency true stimulation
low brain structure retention group 2:high frequency true stimulation
low brain structure retention group 3:pseudo-stimulation

Sponsors

The First Affiliated Hospital of Ji'nan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: The first stroke met the diagnostic criteria of cerebral infarction or cerebral hemorrhage adopted by the 4th National Conference on Cerebrovascular Diseases. The lesions were confirmed by CT or MRI in the left cerebral hemisphere. 1) The results of WAB were non-fluent aphasia. 2) The age of the patient was 40-70 years old. 3) The course of disease ranged from 6 months to 18 months. 4) Above primary school education, the right-handedness was determined by the criterion of handedness in Department of Neurology, First Hospital of Beijing Medical University. 5) Clear mind, stable condition, no serious cognitive impairment, normal language and intelligence before onset; 6) Be able to accept and cooperate with MRI examination and language function evaluation, and the patients and their families sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Language, reading and writing disorders caused by severe sensory and motor organ damage such as hearing, vision, writing and pronunciation; 2) Those with learning difficulties and language deficits caused by congenital or juvenile diseases; 3) Complicated with epilepsy, severe heart, liver, kidney dysfunction or other serious somatic diseases; 4) History of mental disorders in the past; 5) Metal foreign bodies or other electronic devices implanted into the body.

Design outcomes

Primary

MeasureTime frame
MRI;

Countries

China

Contacts

Public ContactDai Yanhong

The First Affiliated Hospital of Ji'nan University

1392614813@qq.com+86 15521207788

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026