Osteoarthritis of the knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who received unilateral total knee arthroplasty for the first time; 2. The patient is between 50 and 80 years old and can communicate with each other normally to help collect information; 3. the American society of anesthesiologists (ASA) classification I to III level.
Exclusion criteria
Exclusion criteria: 1. Patients who did not sign the informed consent for clinical trials and refused to participate in this study; 2. Previous allergies to any of the drugs used in the study; 3. There are any contraindications associated with nerve block local anesthesia; 4. There are neuromuscular lesions in the surgical limb that affect the limb muscle strength of the patient; 5. Morbidly obese patients (BMI>=40Kg/m2); 6. Patients who cannot communicate normally or cooperate with information collection; 7. Secondary surgery patients and patients with related contraindications of surgical anesthesia; 8. Patients with long-term high opioid use and long-term chronic pain; 9. with history of anaesthetic allergy or blocking lateral nerve damage; 10. with history of serious liver and kidney dysfunction or mental illness; 11. with history of drug dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score at rest and dynamic acitivity at Postoperative PACU, 24h, 48h, 72h;the Bromage score;The Quadriceps muscle strength score;The walking distance; the incidence of postoperative remedial analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative sufentanil dosage;Intraoperative vital signs changes; | — |
Countries
China
Contacts
Affiliated Hospital of Qingdao University