Discogenic Sciatica
Conditions
Interventions
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Unilateral leg pain diagnosed as discogenic sciatica and leg pains that correlate with CT or MRI findings of lumbar disc herniation; 2. Sciatica patients with an average leg pain VAS of 40 mm or higher in the last 24 hours; 3. Aged 18 to 75 years; 4. Patients who agree to follow the trial protocol.
Exclusion criteria
Exclusion criteria: 1. Severe cases with central or giant or ruptured lumbar disc herniation, cauda equina syndrome, foot drop, or surgery requirements; 2. Progressive neurological symptoms after 3 months of strict conservative treatment (e.g., nerve root adhesion, crossed straight-leg testing, or obvious muscle atrophy); 3. Severe cardiovascular, liver, kidney, hematopoietic system diseases, autoimmune diseases, or poor nutritional status; 4. Subjects with cognitive impairment; 5. Subjects who received acupuncture for sciatica within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change from baseline in mean weekly VAS of leg pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in mean weekly VAS of low back pain;Brief Pain Inventory;Oswestry disability index;Short Form 36-item Health Survey(SF-36);Serum mitochondrial DNA concentration; | — |
Countries
China
Contacts
Public ContactWang Ke
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed