Effects of Body Fat Percentage on EC50 of propofol for successful laryngeal mask insertion

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900026263

Enrollment

Unknown

Registered

2019-09-28

Start date

2019-11-01

Completion date

Unknown

Last updated

2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Selective surgery

Interventions

normal weight group:Propofol dose

Obesity group:Propofol dose

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. ASA I to III; 2. Selective orthopaedic, gynecological and general surgery under general anesthesia; 3. Aged 30~65 years; 4. Patient and their family members have signed informed consent for anesthesia; 5. Height and sex are not limited.

Exclusion criteria

Exclusion criteria: 1. Potentially difficult airways; 2. Neurological ,psychiatric diseases, circulatory and respiratory diseases existed before operation; 3. Preoperative liver and kidney dysfunction existed; 4. History of gastroesophageal reflux; 5. History of alcohol and drug abuse; 6. History of allergies to opioids and propofol or other fat emulsions; 7. Pregnant or lactating women; 8. Pathological obesity.

Design outcomes

Primary

Measure	Time frame
Plasma concentration;Effector concentration;	—

Countries

China

Contacts

Public ContactLi Jiyuan

Leslie_Lee068@163.com+86 13924892016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026