stroke
Conditions
Interventions
Sponsors
National Natural Science Foundation of China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The first cerebral infarction which accords with the diagnosis standard of Chinese and Western medicine and belongs to unilateral brain; 2. Aged 20-75 years, regardless of gender; 3. Right-handed; 4. The onset was more than 1 month and less than 2 years. 5. Primary school and above education level; 6. No severe aphasia (Aphasia Screening Scale); 7. Simple Mental State Scale screening results showed that there was no cognitive impairment. 8. The degree of motor dysfunction of affected limbs was Brunnstrom grade II-VI. 9. It has certain motor imagery function. The motor imagery questionnaire has 25 points or more. 10. Can tolerate half an hour to one hour of training or testing; 11. Volunteer to participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Neurological diseases, including epilepsy, which seriously affect the completion of the trial program. 2. there are contraindications of MRI, such as pacemaker, metal implant, etc. 3. Excessive pain exists in limb joints. 4. Cranial fractures and/or severe head injuries; 5. History of head and/or brain surgery; 6. Severe visual or auditory impairment, unable to cooperate with training; 7. Three cycles of antidepressants and psychotropic tranquilizers were taken 30 days before the trial. 8. Other drugs to reduce seizure threshold were taken 30 days before the trial. 9. Severe diseases of liver, kidney, heart, lung and blood system were found. 10. Excessive sensitivity or mental illness; 11. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer motor assessment upper extremity scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| modified Barthel index, MBI;Berg balance scale, BBS;Fugl-Meyer motor assessment Lower extremities scale;Beck depression inventory, BDI;World Health Organization Quality of Life Assessment Instrument Brief Version, WHOQOL-BREF;Functional magnetic resonance imaging;Structural Brain Imaging; | — |
Countries
China
Contacts
Public ContactChunlei Shan
Shanghai University of Traditional Chinese Medicine
Outcome results
None listed