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Effect of optimized thoracic paravertebral nerve block on early and rapid recovery and long-term clinical outcome of radical lung cancer patients

Effect of optimized thoracic paravertebral nerve block on early and rapid recovery and long-term clinical outcome of radical lung cancer patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026213
Enrollment
Unknown
Registered
2019-09-26
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

Sevoflurane+TPVB:Sevoflurane+TPVB
Sevoflurane+Optimized TPVB:Sevoflurane+Optimized TPVB
Propfol:Propofol
Propofol+TPVB:Propofol+TPVB
Propofol+Optimized TPVB:Propofol+Optimized TPVB

Sponsors

Henan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with elective thoracoscopic radical lung cancer surgery; 2. Aged 18-64 years, body mass index 18-25kg/m2; 3. ASA grade II or III; 4. 80% estimated value of forced lung capacity >, 70% estimated value of expiratory rate > in the first second; 5. Definite preoperative diagnosis of lung cancer, tumor diameter greater than 1cm. 6. Willing to participate in the trial and sign infored consent.

Exclusion criteria

Exclusion criteria: 1. Communication disorders, inability to cooperate with researchers, such as language comprehension disorders, mental disorders, etc.; 2. Preoperative history of chemoradiotherapy; 3. Serious cardiovascular and cerebrovascular diseases; 4. History of diabetes, blood diseases and other metabolic disorders; 5. History of hypertension, no chronic obstructive or (and) restrictive lung disease; 6. Smoking history within 2 weeks before surgery; 7. Previous history of other operations.

Design outcomes

Primary

MeasureTime frame
Stay duration in hospital;

Secondary

MeasureTime frame
Disease-free survival;Overall survival;Life quality;postoperative complications;Patient Satisfaction;Incidence of chronic pain;Hospital cost;Tumor microenviromental marker;

Countries

China

Contacts

Public ContactZhang Wei

Henan Provincial People's Hospital

myhope2005@163.com+86 13838299702

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 25, 2026