congenital diaphragmatic hernia in neonates
Conditions
Interventions
Delayed operation time Group:Left diaphragmatic hernia repair under thoracoscope
Shift to an earlier operation time group:Left diaphragmatic hernia repair under thoracoscope
Sponsors
Guangdong Women and Children Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A patient meeting all the following criteria should be included in this study: prenatal ultrasound assessments indicated left-sided CDH; Level III obstetric ultrasound indicating LHR > 1.0 during 24-28 weeks of pregnancy; diagnosed with CDH and transferred from the Department of Obstetrics to the NICU of the Department of Pediatric Thoracic Surgery after delivery between September 5, 2017 and December 31, 2027
Exclusion criteria
Exclusion criteria: A patient should be rendered ineligible for this study when meeting any of the following criteria: prenatal ultrasound assessments indicated right-sided diaphragmatic hernia; Level III obstetric ultrasound indicating LHR = 1.0 during 24-28 weeks of pregnancy;diagnosed with other heart malformations than incomplete closure of patent ductus arteriosus (PDA) and patent foramen ovale (PFO); transferred to our hospital after delivery in another hospital
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LHR;LHR-based mild/moderate CDH ratio;days of pregnancy;natural labor/C-section ratio;male/female ratio;birth weight;Apgar score at 1 minute after birth;preoperative PAH-free/mild PAH ratio;age when receiving surgery (duration of preoperative mechanical ventilation);operation duration;hernia sac-free/hernia sac ratio;duration of postoperative mechanical ventilation;postoperative drainage volume;duration of postoperative drainage;postoperative pulmonary infection rate;incision infection rate;duration of using antibiotics;duration of fasting;incidence of postoperative moderate-to-severe PAH;incidence of postoperative GERD (gastric acid retention);postoperative mortality;hospital stay;hospitalization costs;recurrence rate during follow-ups; | — |
Countries
China
Contacts
Public ContactLiu QianLi
Department of Pediatric General Thoracic Surgery, Guangdong Women and Children Hospita
Outcome results
None listed