The relationship between the changes of growth hormone-insulin-like growth factor axis and intestinal flora imbalance in obese children

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900026171

Enrollment

Unknown

Registered

2019-09-24

Start date

2019-09-16

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

obese group:none

control group:none

Eligibility

Sex/Gender

All

Age

5 Years to 14 Years

Inclusion criteria

Inclusion criteria: The body mass index (BMI) is greater than 95 percent of normal weight children. Control subjects which include children and adolescents, were recruited from a populationof non-obese healthy children and adolescents.

Exclusion criteria

Exclusion criteria: 1. hypothalamic or pituitary disorders, hypothyroidism, adrenal dysfunction; 2. diabetes mellitus,chromosome abnormalities or all sorts of syndromes; 3. hepatitis B or C, serious infection, systemic disease and other chronic wasting illnesses; 4. the use of drugs may influence body composition, GH secretion or glucose and lipid metabolism; 5. short stature or the growth velocity is less than 5 cm/year.

Design outcomes

Primary

Measure	Time frame
GH stimulating tests;IGF-1;16SrRNA gene amplification and sequencing;Liver function,lipid,and FBG;	—

Countries

China

Contacts

Public ContactLiang Shuang

The Second Hospital of Shandong University

liangshuang3508@163.com+86 17660082768

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026