Premenstrual dysphoric disorder (PMDD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The susbjects in line with ICD-10 depressive episode diagnostic criteria, and mild or moderate; 2. Aged 18 to 45 years; 3. The subjects with clear consciousness and independent judgment; 4. The subjects can understand the purpose of this study and voluntarily coordinate; 5. The subjects had no major diseases such as heart, liver, brain tumor and other brain disease, taking the history of psychotropic substances.
Exclusion criteria
Exclusion criteria: 1. Psychiatric patients; 2. The subjects had serious physical disease; 3. The subjects had a history of drug abuse including to take drugs treatment PMDD within three months; 4. The subjects had blood diseases; 5. The subjects were pregnant or lactating women; 6. The subjects had the symptoms of aphasia, disturbance of consciousness, dementia and other conditions; 7. The subjects had history of chronic five viscera diseases and clinical symptoms; 8. The subjects had unilateral oophorectomy or abortion within six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DRSP;HAMD;HAMA;PMDD Liver Qi Inverse Syndromes Severity Evaluation Scale;PMDD Liver Qi Depression Syndromes Severity Evaluation Scale;5-HT;NE;AGT ?;GC;melatonin;progesterone;E2;PRL;FSH;TSH;FMRI; | — |
Countries
China
Contacts
Shandong University of Traditional Chinese Medicine