colorectal cancer
Conditions
Interventions
experimental group:ketoacetate aminobutanol prophylactic analgesia
control group:normal saline
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Shihezi University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. BMI:1825kg/m2; 3. ASA classification level I-II; 4. Preoperative pathology demonstrated colorectal cancer; 5. The patient himself is informed and signs or the family signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Abnormal liver and kidney function, cardiopulmonary insufficiency, or with a history of severe cardiovascular, endocrine system or liver and kidney disease; 2. gastrointestinal ulcer, 3. history of blood system diseases and bleeding, 4. allergy of non-steroidal painkillers, 5. with a history of using mental drugs, opioids or non-steroidal anti-inflammatory drugs; 6. history of long-term hormone use; 7. receiving immunosuppressant and cytological treatment; 8. history of alcohol consumption; 9. history of perioperative transfusion; 10. mental and communication disorders. 11. The length of operation was >= 4 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QOR-40 score;Tcr cdr3 length;TCRV; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex;age;Height;Weight;ASA classification;Operation time;Intraoperative blood loss;Extubation time;PONV;VAS score;Discharge time;Analgesic remedial measures;IL-1ß;IL-6;IL-10;CD3+;CD4+;CD8+; | — |
Countries
China
Contacts
Public ContactTao Jun
Department of Anesthesiology, the First Affiliated Hospital of Shihezi University Medical College
Outcome results
None listed