Hypothalamic pituitary disease
Conditions
Interventions
1+2+3:Growth hormone group, Letrozole group, Growth hormone combined with Letrozole group
Sponsors
Affiliated Hospital of Jining Medical University
Eligibility
Sex/Gender
Male
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Aged 12-18 years (into adolescence); gender: male; bone age: 13.5-16 years old; height: the same age and same sex with the same race average height -2SD, 2 according to the bone age height standard deviation below -2SD, or adults with a lifetime expectancy of < 160cm are predicted.
Exclusion criteria
Exclusion criteria: Asexual development; combined with thyroid disease, abnormal bone metabolism, chronic liver and kidney disease, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Height; | — |
Countries
China
Contacts
Public ContactBo Ban
Affiliated Hospital of Jining Medical University
Outcome results
None listed