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Evaluation of analgesic effect of dexmedetomidine combined with ropivacaine for lumbar muscle block in patients undergoing total hip arthroplasty

Evaluation of analgesic effect of dexmedetomidine combined with ropivacaine for lumbar muscle block in patients undergoing total hip arthroplasty

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026129
Enrollment
Unknown
Registered
2019-09-22
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip dysfunction

Interventions

A:quadratus lumborum block with 0.33% ropivacaine
B:quadratus lumborum block with 0.33% ropivacaine combined with 1 ug/kg dexmedetomidine
C:quadratus lumborum block with 0.25% ropivacaine combined with 1 ug/kg dexmedetomidine
D:quadratus lumborum block with 0.25% ropivacaine combined with 0.75ug/kg dexmedetomidine

Sponsors

Department of Anesthesiology, First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 20 elderly patients with total hip arthroplasty under general anesthesia in the First Affiliated Hospital of Chongqing Medical University, aged 45-85 years, with body mass 45-70 kg, American Society of Anesthesiologists (ASA) Grade I-III.

Exclusion criteria

Exclusion criteria: Obvious dysfunction of heart, brain, lung, liver and kidney; mental patients, local skin infection at puncture site, peripheral neuropathy, coagulopathy, opioid abuse, chronic pain, unable to match visual analogue scale (VAS). Patients taking adrenergic blockers; hypertensive patients whose drugs are uncontrollable; patients with bradycardia; those with unexpected medications such as drug allergies and major bleeding during surgery; others who cannot tolerate this experiment.

Design outcomes

Primary

MeasureTime frame
Sports VAS score;Muscle recovery time;Total amount of tramadol;PCIA pump press times;

Secondary

MeasureTime frame
Resting VAS score;Ramsay??;Incidence of nausea and vomiting;Incidence of sinus bradycardia;

Countries

China

Contacts

Public ContactKaihua He

Department of Anesthesiology, First Affiliated Hospital of Chongqing Medical University

13908396469@163.com+86 13908396469

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026