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Comparison of single inhalation of sevoflurane with intranasal ketamine as rescue techniques for failed intranasal dexmedetomidine sedation in 1- to 6-year-old children undergoing magnetic resonance imaging: A randomized trial

Comparison of single inhalation of sevoflurane with intranasal ketamine as rescue techniques for failed intranasal dexmedetomidine sedation in 1- to 6-year-old children undergoing magnetic resonance imaging: A randomized trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026118
Enrollment
Unknown
Registered
2019-09-22
Start date
2019-12-01
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric MRI sedation

Interventions

Group S:single inhalation of 6% sevoflurane with a mask
Group K:intranasal ketamine 2 mg/kg

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: Patients corresponding to ASA physical status I or II, aged between 1 and 6 years, who failed intranasal dexmedetomidine sedation during routine clinical diagnostic 3.0 T MRI scanning, i.e., at 30 min postadministration, with no evidence of sedation, as assessed using the Modified Observer Assessment of Alertness and Sedation Scale were included in this trial

Exclusion criteria

Exclusion criteria: Exclusion criteria were allergy to any drug included in the protocol or the presence of contraindications to their use, a recent respiratory infection or episode of acute asthma in the preceding 2 weeks, difficult airway or risk of upper airway obstruction, behavioral problems, gastroesophageal reflux disease, intracranial hypertension or serious neurological impairment, cardiac arrhythmia and known congenital heart disease.

Design outcomes

Primary

MeasureTime frame
sucess rate;induction time;scan time;recovery time;time to return to baseline functional status ;occurrence of adverse events;Satisfaction score;

Countries

China

Contacts

Public ContactLiu Wei

Children's Hospital of Chongqing Medical University

faithrefresh@126.com+86 15123201847

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026